AES Antibody - middle region : Biotin (ARP32323_P050-Biotin)

Product Specifications

Gene Name

Amino-terminal enhancer of split

Gene Aliases

AES, GRG, ESP1, GRG5, AES-1, AES-2, Grg-5

Gene ID

166

Swiss Prot

Q14CJ1

Accession Number

NP_945320

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human AES

Target

AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

MFAP1; MBNL1; SMAD3; LMO2; LMO1; KRT31; DDX6; CRX; BYSL; BCL6; AES; AEN; CARD9; PARVG; LSM2; HOMEZ; MAGOHB; RNF31; VPS37C; C1orf109; OSGIN1; MED4; PRPF31; GORASP2; KANK2; LDOC1; MTUS2; DIP2A; NCDN; BAHD1; IKZF3; U2AF2; RBPMS; FRS3; NEK6; CALCOCO2; ABI2; T

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

AES is supported by BioGPS gene expression data to be expressed in DU145

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.