AES Antibody - middle region: FITC (ARP32323_P050-FITC)
Product Specifications
Gene Name
Amino-terminal enhancer of split
Gene Aliases
AES, GRG, ESP1, GRG5, AES-1, AES-2, Grg-5
Gene ID
166
Swiss Prot
Q14CJ1
Accession Number
NP_945320
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human AES
Target
AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
MFAP1; MBNL1; SMAD3; LMO2; LMO1; KRT31; DDX6; CRX; BYSL; BCL6; AES; AEN; CARD9; PARVG; LSM2; HOMEZ; MAGOHB; RNF31; VPS37C; C1orf109; OSGIN1; MED4; PRPF31; GORASP2; KANK2; LDOC1; MTUS2; DIP2A; NCDN; BAHD1; IKZF3; U2AF2; RBPMS; FRS3; NEK6; CALCOCO2; ABI2; T
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
AES is supported by BioGPS gene expression data to be expressed in DU145
Concentration
0.5 mg/mL
Homology
Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
29kDa
Shipping Conditions
Wet Ice
Protein Length
264
NCBI Gene Symbol
AES
Protein Name
Amino-terminal enhancer of split
Nucleotide Accession Number
NM_198969
Curated Selection
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