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GLI3 Antibody : FITC (ARP32317_P050-FITC)

Selected Variant

ARP32317_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

GLI family zinc finger 3

Gene Aliases

PHS, ACLS, GCPS, PAPA, PAPB, PAP-A, PAPA1, PPDIV, GLI3FL, GLI3-190

Gene ID

2737

Swiss Prot

P10071

Accession Number

NP_000159

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence KPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGC

Target

This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.

Partner Proteins

ZIC3; SOX2; UBC; BTRC; PRKCA; GSK3A; CSNK1A1; SKI; HDAC1; MED12; CREBBP; STK36; SUFU; SMAD3; ZIC2; TWIST1; SMAD1; SMAD2; SMAD4; ZIC1; Sin3a; Shh; SAP18; Pias1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

170 kDa

Shipping Conditions

Wet Ice

Protein Length

1580

NCBI Gene Symbol

GLI3

NCBI GB Accession Number

GLI3

Host or Source

Rabbit

Protein Name

Transcriptional activator GLI3

Nucleotide Accession Number

NM_000168

Peptide Sequence

KPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGC

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