MMP19 Antibody - N-terminal region : Biotin (ARP32314_P050-Biotin)
Product Specifications
Gene Name
Matrix metallopeptidase 19
Gene Aliases
CODA, MMP18, RASI-1
Gene ID
4327
Swiss Prot
Q99542
Accession Number
NP_002420
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MMP19
Target
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP-19 has not been determined. This gene corresponding to this protein was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19) . Multiple transcript variants encoding distict isoforms have been identified for this gene.
Partner Proteins
ACAN
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
References & Citations
Sadowski, T., et al., (2003) Mol.Biol.Cell14 (11),4569-4580
Shipping Conditions
Wet Ice
Protein Length
508
NCBI Gene Symbol
MMP19
NCBI GB Accession Number
MMP19
Host or Source
Rabbit
Protein Name
Matrix metalloproteinase-19
Nucleotide Accession Number
NM_002429
Peptide Sequence
ALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWR
Frequently Asked Questions
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