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MMP19 Antibody - N-terminal region : Biotin (ARP32314_P050-Biotin)

Product Specifications

Gene Name

Matrix metallopeptidase 19

Gene Aliases

CODA, MMP18, RASI-1

Gene ID

4327

Swiss Prot

Q99542

Accession Number

NP_002420

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MMP19

Target

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP-19 has not been determined. This gene corresponding to this protein was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19) . Multiple transcript variants encoding distict isoforms have been identified for this gene.

Partner Proteins

ACAN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Sadowski, T., et al., (2003) Mol.Biol.Cell14 (11),4569-4580

Shipping Conditions

Wet Ice

Protein Length

508

NCBI Gene Symbol

MMP19

NCBI GB Accession Number

MMP19

Host or Source

Rabbit

Protein Name

Matrix metalloproteinase-19

Nucleotide Accession Number

NM_002429

Peptide Sequence

ALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWR

Frequently Asked Questions

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