SCMH1 Antibody - middle region : Biotin (ARP32298_P050-Biotin)

Product Specifications

Gene Name

Sex comb on midleg homolog 1 (Drosophila)

Gene Aliases

Scml3

Gene ID

22955

Swiss Prot

Q96GD3-4

Accession Number

NP_036368

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SCMH1

Target

SCMH1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Partner Proteins

UBQLN1; RNF2; MAGEA12; BMI1; UBQLN4; PHC3; CBX4; PCGF2; PHC2; PHC1; MAML3; LZTR1; PCBD1; EWSR1; TMEM11; SCMH1; MOB4; TOB1; POLR2M; LYPLA2; GMNN; HK1; Cbx2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.