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PQBP1 Antibody - middle region : HRP (ARP32280_P050-HRP)

Selected Variant

ARP32280_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Polyglutamine binding protein 1

Gene Aliases

SHS, MRX2, MRX55, MRXS3, MRXS8, NPW38, RENS1

Gene ID

10084

Swiss Prot

O60828

Accession Number

NP_001027555

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PQBP1

Target

This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Partner Proteins

MAPRE1; GOLGA2; LZTS2; UBC; APBB1; WDR77; AQR; HNRNPH2; MRPL53; SLIRP; SRPRB; SUGP1; MRPS28; RPS6KA6; HRSP12; SCO2; ZC3H11A; UBL4A; VDAC3; RRBP1; RPS28; RBMS1; NDUFA7; IDH3G; APP; WBP11; RCVRN; LNX1; SF3A2; SFTPC; TXNL4A; TLX3; LRIF1; MED31; POLR2A; C14or

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Lim, J., (2006) Cell 125 (4), 801-814

Shipping Conditions

Wet Ice

Protein Length

265

NCBI Gene Symbol

PQBP1

NCBI GB Accession Number

PQBP1

Host or Source

Rabbit

Protein Name

Polyglutamine-binding protein 1

Nucleotide Accession Number

NM_001032383

Peptide Sequence

LVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHDKSDRGHDKSDRSH

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