NR2E3 Antibody - middle region: Biotin (ARP32262_P050-Biotin)

This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

BCL11A; SIN3A; DHX30; TBL3; MYBBP1A; NCOR1; HDAC3; RBL1; RBBP7; RBBP4; HDAC1; CDK9; VDR; DEDD2; RBFOX2; IRF9; ZNF232; SNAPC1; PPARG; HOXC13; NR3C1; ELAVL2; POLR3D; RARA; NR1D1; CRX; RXRB; RXRA

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.