RNF12 Antibody - C-terminal region : Biotin (ARP32151_P050-Biotin)

Product Specifications

Gene Name

Ring finger protein, LIM domain interacting

Gene Aliases

MRX61, RNF12, TOKAS, NY-REN-43

Gene ID

51132

Swiss Prot

Q9NVW2

Accession Number

NP_057204

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RNF12

Target

RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.

Partner Proteins

STMN1; SNX17; UBC; RPS14; TNFAIP3; UBE2D1; LNX2; TERF1; SMURF2; HHV8GK18_gp81; HDAC2; REXO1; TOLLIP; LDB1; UBXN1; UBE2E2; SIAH1; SS18L1; STAT6; UBE2D4; UBE2E1; UBE2D3; UBE2D2; LDB2; SIN3A; PDLIM1; LHX1; LHX2; LIMK1; LHX3; ISL1; LMO2; RLIM; ESR1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

RLIM is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%; Yeast: 89%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.