RNF12 Antibody - C-terminal region : FITC (ARP32151_P050-FITC)

Product Specifications

Gene Name

Ring finger protein, LIM domain interacting

Gene Aliases

MRX61, RNF12, TOKAS, NY-REN-43

Gene ID

51132

Swiss Prot

Q9NVW2

Accession Number

NP_057204

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RNF12

Target

RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.

Partner Proteins

STMN1; SNX17; UBC; RPS14; TNFAIP3; UBE2D1; LNX2; TERF1; SMURF2; HHV8GK18_gp81; HDAC2; REXO1; TOLLIP; LDB1; UBXN1; UBE2E2; SIAH1; SS18L1; STAT6; UBE2D4; UBE2E1; UBE2D3; UBE2D2; LDB2; SIN3A; PDLIM1; LHX1; LHX2; LIMK1; LHX3; ISL1; LMO2; RLIM; ESR1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

RLIM is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%; Yeast: 89%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.