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Wnt1 Antibody - C-terminal region : FITC (ARP32123_P050-FITC)

Selected Variant

ARP32123_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Wingless-type MMTV integration site family, member 1

Gene Aliases

Sw, Int, Wnt-, Int-1, Wnt-1, swaying

Gene ID

22408

Swiss Prot

P04426

Accession Number

NP_067254

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Wnt1

Target

Wnt1 is a ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, it is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. It is a probable developmental protein and may be a signaling molecule important in CNS development. Wnt1 is likely to signal over only few cell diameters. It ha s a proeminent role in the induction of the mesencephalon and cerebellum. It may play a crucial role in the morphogenesis of the neural tube and/or the early stages of CNS development. It has a role in osteoblast function and bone development.

Partner Proteins

Lrp6-b; Lrp6; Wnt3a; Porcn; Ryk; Lrp5; Fzd8; Fzd1; Dkk1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

Shipping Conditions

Wet Ice

Protein Length

370

NCBI Gene Symbol

WNT1

NCBI GB Accession Number

Wnt1

Host or Source

Rabbit

Protein Name

Proto-oncogene Wnt-1

Nucleotide Accession Number

NM_021279

Peptide Sequence

NFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCN

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