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PIK3CB Antibody - C-terminal region : Biotin (ARP32117_T100-Biotin)

Product Specifications

Gene Name

Phosphoinositide-3-kinase, catalytic, beta polypeptide

Gene Aliases

PI3K, PIK3C1, P110BETA, PI3KBETA

Gene ID

5291

Swiss Prot

Q24JU2

Accession Number

NP_006210

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PIK3CB

Target

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993) .[supplied by OMIM].

Partner Proteins

EGFR; IRS1; GRB2; PIK3R1; GAB2; PIK3R2; CRK; CBL; RAB5A; UBC; ALAS1; HPS6; DVL3; ALK; AGTR2; PRKCD; PRKCE; YWHAQ; HCK; MME

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

123kDa

References & Citations

Zhao, J.J., et al., (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (51), 18443-18448

Shipping Conditions

Wet Ice

Protein Length

1070

NCBI Gene Symbol

PIK3CB

NCBI GB Accession Number

PIK3CB

Host or Source

Rabbit

Protein Name

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

Nucleotide Accession Number

NM_006219

Peptide Sequence

VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKD

Subunit

Beta isoform

Frequently Asked Questions

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