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FOXO4 Antibody - C-terminal region : FITC (ARP32110_P050-FITC)

Selected Variant

ARP32110_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Forkhead box O4

Gene Aliases

AFX, AFX1, MLLT7

Gene ID

4303

Swiss Prot

P98177

Accession Number

NP_005929

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human FOXO4

Target

FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.

Partner Proteins

REL; SFN; AKT1; OGT; UBC; ATXN3; MDM2; NLK; USP7; CTNNB1; CREBBP; VDR; SIRT1; SMAD3; XPO1; YWHAZ; SMAD4; FOXG1; AKT2; ESR1; PIN1; CCND1; CDKN1A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

Shipping Conditions

Wet Ice

Protein Length

505

NCBI Gene Symbol

FOXO4

NCBI GB Accession Number

FOXO4

Host or Source

Rabbit

Protein Name

Forkhead box protein O4

Nucleotide Accession Number

NM_005938

Peptide Sequence

TPVLTPPTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFN

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