DVL1 Antibody - middle region: FITC (ARP32100_T100-FITC)
Product Specifications
Gene Name
Dishevelled, dsh homolog 1 (Drosophila)
Gene Aliases
DVL, DRS2, DVL1L1, DVL1P1
Gene ID
1855
Swiss Prot
A6NKG8
Accession Number
EAW56226
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DVL1
Target
DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Partner Proteins
NCK2; TRIM69; NUMA1; HUWE1; UBC; DVL2; WWOX; SIPA1; PSMA3; LRRK2; ITCH; HECW1; NEDD4; ANXA7; SDC4; NKD2; CYLD; SIRT1; CCDC88C; VANGL1; CXXC4; PPM1A; DYNLT1; HDHD2; BRD7; DAAM1; AXIN1; USP13; SMAD3; SMAD7; FRAT1; RAC1; DVL3; SMAD2; DVL1; SMAD4; CSNK1D; CSN
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Sample Type
DVL1 is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 87%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
38kDa
Shipping Conditions
Wet Ice
Protein Length
353
NCBI Gene Symbol
DVL1
Nucleotide Accession Number
NM_004421
Curated Selection
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