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DVL1 Antibody - middle region : FITC (ARP32100_T100-FITC)

Selected Variant

ARP32100_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Dishevelled, dsh homolog 1 (Drosophila)

Gene Aliases

DVL, DRS2, DVL1L1, DVL1P1

Gene ID

1855

Swiss Prot

A6NKG8

Accession Number

EAW56226

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DVL1

Target

DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Partner Proteins

NCK2; TRIM69; NUMA1; HUWE1; UBC; DVL2; WWOX; SIPA1; PSMA3; LRRK2; ITCH; HECW1; NEDD4; ANXA7; SDC4; NKD2; CYLD; SIRT1; CCDC88C; VANGL1; CXXC4; PPM1A; DYNLT1; HDHD2; BRD7; DAAM1; AXIN1; USP13; SMAD3; SMAD7; FRAT1; RAC1; DVL3; SMAD2; DVL1; SMAD4; CSNK1D; CSN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Sample Type

DVL1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 87%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

Shipping Conditions

Wet Ice

Protein Length

353

NCBI Gene Symbol

DVL1

NCBI GB Accession Number

DVL1

Host or Source

Rabbit

Nucleotide Accession Number

NM_004421

Peptide Sequence

LKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNK

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