PAWR Antibody - middle region : Biotin (ARP32062_P050-Biotin)
Product Specifications
Gene Name
PRKC, apoptosis, WT1, regulator
Gene Aliases
PAR4, Par-4
Gene ID
5074
Swiss Prot
O75796
Accession Number
NP_002574
Host
Rabbit
Reactivity
Human, Mouse, Rat, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PAWR
Target
The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
Partner Proteins
FBXO45; UBC; EED; FAM129B; SNX6; CAND1; VPS29; JMJD6; STAT1; SNX2; SHMT2; SHMT1; PPM1G; IDE; H3F3A; CARS; ATP6V1C1; APEH; PAN2; DRD2; DAPK3; SQSTM1; PRKCZ; Spsb4; Spsb2; SPSB1; FBXO25; HSPA5; Cep350; Kif23; THAP1; SLC5A7; AATF; TFPT; PAWR; WT1; RRAS2; ATP
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
37kDa
References & Citations
Bergmann, M., et al., (2004) Ann.Hematol.83 (10),646-653
Shipping Conditions
Wet Ice
Protein Length
340
NCBI Gene Symbol
PAWR
NCBI GB Accession Number
PAWR
Host or Source
Rabbit
Protein Name
PRKC apoptosis WT1 regulator protein
Nucleotide Accession Number
NM_002583
Peptide Sequence
VNIPAAECLDEYEDDEAGQKERKREDAITQQNTIQNEAVNLLDPGSSYLL
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