NKX3-1 Antibody - middle region : Biotin (ARP32045_P050-Biotin)
Product Specifications
Gene Name
NK3 homeobox 1
Gene Aliases
NKX3, BAPX2, NKX3A, NKX3.1
Gene ID
4824
Swiss Prot
Q99801
Accession Number
NP_006158
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1
Target
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
STRA13; CHPF; AEN; RABL6; TEX264; STMN3; LMCD1; SPDEF; CKAP4; HNRNPA0; CCT7; HMG20B; FEM1B; HSP90B1; TPT1; RPL37A; RARG; PTMS; PEBP1; ND4; MNAT1; MAN2B1; RPSA; TOP1; WDR77; TOPORS; KAT2B; SP5; SP4; SP3; SP2; SP1; HDAC1; HIPK2; SRF
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 86%; Guinea Pig: 85%; Horse: 79%; Human: 100%; Rabbit: 79%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
26kDa
References & Citations
Possner, M., (2008) Int. J. Oncol. 32 (4), 877-884
Shipping Conditions
Wet Ice
Protein Length
234
NCBI Gene Symbol
NKX3-1
NCBI GB Accession Number
NKX3-1
Host or Source
Rabbit
Protein Name
Homeobox protein Nkx-3.1
Nucleotide Accession Number
NM_006167
Peptide Sequence
KRKQLSSELGDLEKHSSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSW
Frequently Asked Questions
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