NFKB2 Antibody - C-terminal region: FITC (ARP32043_P050-FITC)
Product Specifications
Gene Name
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Gene Aliases
P52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100
Gene ID
4791
Swiss Prot
Q00653
Accession Number
NP_002493
Host
Rabbit
Reactivity
Human, Rat, Cow, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human NFKB2
Target
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Partner Proteins
FBXW11; UBC; RELB; RELA; REL; NFKB1; CHUK; BCL3; SUMO1; NEDD8; TNFAIP3; BIRC2; EPS8; VCP; UBD; BRRF1; COMMD1; COMMD2; MAP3K14; BTRC; NFKB2; FBXW7; TSG101; IKBKG; SUMO2; DPF2; PSMD11; NFKBIZ; TNIP2; HDAC5; NFKBIB; HDAC4; USP2; NFKBIE; RPL6; IKBKB; TSC22D3
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 77%; Horse: 85%; Human: 100%; Pig: 77%; Rabbit: 92%; Rat: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
97kDa
Shipping Conditions
Wet Ice
Protein Length
900
NCBI Gene Symbol
NFKB2
Protein Name
Nuclear factor NF-kappa-B p100 subunit
Nucleotide Accession Number
NM_002502
Curated Selection
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