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MYCN Antibody - C-terminal region : FITC (ARP32030_T100-FITC)

Selected Variant

ARP32030_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

Gene Aliases

NMYC, ODED, MODED, N-myc, bHLHe37

Gene ID

4613

Swiss Prot

P04198

Accession Number

NP_005369

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN

Target

MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas

Partner Proteins

TRIM32; UBC; HDAC5; NMI; MAX; CDKN2A; GRK5; ZBTB17; SIRT1; YEATS4; CSNK1E; FBXW7; PIAS2; AURKA; SP1; NTRK1; NGFR; HDAC2; CSNK2A1; YAF2; MXD1; CSNK2A2; SLC1A2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 77%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Hansford, L.M., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (34), 12664-12669

Shipping Conditions

Wet Ice

Protein Length

464

NCBI Gene Symbol

MYCN

NCBI GB Accession Number

MYCN

Host or Source

Rabbit

Protein Name

N-myc proto-oncogene protein

Nucleotide Accession Number

NM_005378

Peptide Sequence

EDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILER

Price

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