SMAD5 Antibody - middle region : Biotin (ARP32006_P050-Biotin)

Product Specifications

Gene Name

SMAD family member 5

Gene Aliases

DWFC, JV5-1, MADH5

Gene ID

4090

Swiss Prot

Q99717

Accession Number

NP_005894

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SMAD5

Target

SMAD5 undergoes copy number gain and increased expression, rather than loss of expression, and therefore does not act as a tumor-suppressor gene in hepatocellular carcinoma. Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.

Partner Proteins

UBC; SUMO1; HECW2; HBG2; BCAT1; SOX5; SNRPA; SNRNP70; SFPQ; RYR2; RBM4; PTPN12; PSMD11; NEDD4; SMAD4; SMAD1; ANKRD13A; PPIL4; SOX7; SMURF2; SMURF1; MTMR10; CHMP3; CXXC5; SF3B1; U2AF2; PNKP; WWP1; NAA20; EPN1; SMAD3; SMAD2; PAX6; COPS5; HGS; EP300; ELAVL1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.