IRF5 Antibody - middle region : Biotin (ARP31994_P050-Biotin)
Product Specifications
Gene Name
Interferon regulatory factor 5
Gene Aliases
SLEB10
Gene ID
3663
Swiss Prot
Q13568
Accession Number
NP_116032
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human IRF5
Target
IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist.
Partner Proteins
SGTA; IRF5; COPS7B; COPS4; COPS5; COPS6; COPS8; COPS2; COPS3; UBC; GPS1; TRAF6; MYD88; RGS3; PPM1G; IRF6; HIVEP1; GRB2; CHUK; ALPI; MAVS; GTPBP2; CEP152; GTPBP1; SIN3A; NCOR2; NCOR1; KAT2B; HDAC1; EP300; CREBBP; TRIM15; IKBKE; TBK1; IRF3; XPO1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
References & Citations
Clark, H.F., (2008) Arthritis Rheum. 58 (5), 1264-1274
Shipping Conditions
Wet Ice
Protein Length
498
NCBI Gene Symbol
IRF5
NCBI GB Accession Number
IRF5
Host or Source
Rabbit
Protein Name
Interferon regulatory factor 5
Nucleotide Accession Number
NM_032643
Peptide Sequence
IFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQ
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