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IRF5 Antibody - middle region : HRP (ARP31994_P050-HRP)

Product Specifications

Gene Name

Interferon regulatory factor 5

Gene Aliases

SLEB10

Gene ID

3663

Swiss Prot

Q13568

Accession Number

NP_116032

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IRF5

Target

IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist.

Partner Proteins

SGTA; IRF5; COPS7B; COPS4; COPS5; COPS6; COPS8; COPS2; COPS3; UBC; GPS1; TRAF6; MYD88; RGS3; PPM1G; IRF6; HIVEP1; GRB2; CHUK; ALPI; MAVS; GTPBP2; CEP152; GTPBP1; SIN3A; NCOR2; NCOR1; KAT2B; HDAC1; EP300; CREBBP; TRIM15; IKBKE; TBK1; IRF3; XPO1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Clark, H.F., (2008) Arthritis Rheum. 58 (5), 1264-1274

Shipping Conditions

Wet Ice

Protein Length

498

NCBI Gene Symbol

IRF5

NCBI GB Accession Number

IRF5

Host or Source

Rabbit

Protein Name

Interferon regulatory factor 5

Nucleotide Accession Number

NM_032643

Peptide Sequence

IFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQ

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