IRF3 Antibody - C-terminal region : Biotin (ARP31992_P050-Biotin)

IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.

IRF3; UBC; TMEM173; POLR2A; DEAF1; CREBBP; MAFB; vIRF-3; SMAD4; SMAD2; FOXO1; vIRF-1; EP300; SGTA; PEX19; HSP90AA1; PIAS4; TBK1; TOMM70A; TLR2; MAPK9; MAPK8; MAVS; DDX58; TRAF3; ISG15; TRIM21; PIN1; IRF7; HERC5; IKBKE; CUL1; SUMO2; XIAP; HDAC3; SOCS1; RBL

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.