TFAP2E Antibody - N-terminal region : HRP (ARP31976_P050-HRP)
Selected Variant
ARP31976_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
Gene Aliases
AP2E, AP-2epsilon
Gene ID
339488
Swiss Prot
Q6VUC0
Accession Number
NP_848643
Host
Rabbit
Reactivity
Human, Mouse, Cow
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TFAP2E
Target
TFAP2E is the sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 epsilon may play a role in the development of the CNS and in cartilage differentiation
Partner Proteins
UBC
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Human: 100%; Mouse: 92%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
46kDa
References & Citations
Tummala, R., Gene 321, 93-102 (2003)
Shipping Conditions
Wet Ice
Protein Length
442
NCBI Gene Symbol
TFAP2E
NCBI GB Accession Number
TFAP2E
Host or Source
Rabbit
Protein Name
Transcription factor AP-2-epsilon
Nucleotide Accession Number
NM_178548
Peptide Sequence
MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEF
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