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HOXD11 Antibody - middle region : Biotin (ARP31966_P050-Biotin)

Product Specifications

Gene Name

Homeobox D11

Gene Aliases

HOX4, HOX4F

Gene ID

3237

Swiss Prot

A6NIS4

Accession Number

NP_067015

Host

Rabbit

Reactivity

Human, Mouse, Cow, Dog, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HOXD11

Target

HOXD11 belongs to the homeobox family. This family play an important role in morphogenesis in all multicellular organisms. The mouse Hoxd11 plays a role in forelimb morphogenesis.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.

Partner Proteins

MEIS1; HMGB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 92%; Human: 100%; Mouse: 85%; Rabbit: 85%; Sheep: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

References & Citations

Weterman, M.A., (2002) Am. J. Med. Genet. 112 (3), 256-265

Shipping Conditions

Wet Ice

Protein Length

338

NCBI Gene Symbol

HOXD11

NCBI GB Accession Number

HOXD11

Host or Source

Rabbit

Protein Name

Homeobox protein Hox-D11

Nucleotide Accession Number

NM_021192

Peptide Sequence

GFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGSPCT

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