Bilastine
Product Specifications
UNSPSC Description
Bilastine is an oral histamine H1-receptor antagonist. Bilastine can be used for allergic rhinitis and urticaria studies, and it also improves diabetic nephropathy in mice, showing safety for the central nervous system[1][2][3][4].
Target Antigen
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Bilastine.html
Solubility
DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CC(C)(C1=CC=C(CCN2CCC(C3=NC4=CC=CC=C4N3CCOCC)CC2)C=C1)C(O)=O
Molecular Weight
463.61
References & Citations
[1]C. Bachert, et al. Bilastine in allergic rhinoconjunctivitis and urticaria. Allergy.19 May 2010|[2]María Luisa Lucero, et al. Preclinical toxicity profile of oral bilastine. Drug Chem Toxicol. 2012 Jun:35 Suppl 1:25-33.|[3]Roberta Verta, et al. Effect of Bilastine on Diabetic Nephropathy in DBA2/J Mice. Int J Mol Sci. 2019 May 24;20(10):2554.|[4]J Montoro, et al. Bilastine and the central nervous system. J Investig Allergol Clin Immunol. J Investig Allergol Clin Immuno
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14447/Bilastine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14447/Bilastine-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
202189-78-4
Available Sizes
Curated Selection
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