AATF Antibody - N-terminal region : Biotin (ARP31867_P050-Biotin)
Product Specifications
Gene Name
Apoptosis antagonizing transcription factor
Gene Aliases
DED, BFR2, CHE1, CHE-1
Gene ID
26574
Swiss Prot
Q9NY61
Accession Number
NP_036270
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Horse, Rabbit, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human AATF
Target
The AATF gene encodes a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Partner Proteins
MDM2; DAPK3; AR; HIPK2; NGDN; UBC; TSG101; LIN28A; MMS19; ZNF468; NEDD4L; WHSC1; SMAD3; EFNB3; CPD; UBD; CAND1; PIN1; SIRT7; SUMO2; CHEK2; RELA; tat; MAGED1; PCBD2; SS18L1; LZTR1; MPHOSPH6; POLR2J; MPP6; PAWR; DAZAP2; ATR; ATM; CHEK1; LDOC1; SP1; RB1; MAP
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 77%; Horse: 85%; Human: 100%; Mouse: 77%; Rabbit: 100%; Rat: 90%; Yeast: 90%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
63kDa
References & Citations
Burgdorf, S., et al., (2004) J. Biol. Chem. 279 (17), 17524-17534
Shipping Conditions
Wet Ice
Protein Length
560
NCBI Gene Symbol
AATF
NCBI GB Accession Number
AATF
Host or Source
Rabbit
Protein Name
Protein AATF
Nucleotide Accession Number
NM_012138
Peptide Sequence
EEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEE
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