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AATF Antibody - N-terminal region : FITC (ARP31867_P050-FITC)

Selected Variant

ARP31867_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Apoptosis antagonizing transcription factor

Gene Aliases

DED, BFR2, CHE1, CHE-1

Gene ID

26574

Swiss Prot

Q9NY61

Accession Number

NP_036270

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human AATF

Target

The AATF gene encodes a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.

Partner Proteins

MDM2; DAPK3; AR; HIPK2; NGDN; UBC; TSG101; LIN28A; MMS19; ZNF468; NEDD4L; WHSC1; SMAD3; EFNB3; CPD; UBD; CAND1; PIN1; SIRT7; SUMO2; CHEK2; RELA; tat; MAGED1; PCBD2; SS18L1; LZTR1; MPHOSPH6; POLR2J; MPP6; PAWR; DAZAP2; ATR; ATM; CHEK1; LDOC1; SP1; RB1; MAP

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 77%; Horse: 85%; Human: 100%; Mouse: 77%; Rabbit: 100%; Rat: 90%; Yeast: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

63kDa

References & Citations

Burgdorf, S., et al., (2004) J. Biol. Chem. 279 (17), 17524-17534

Shipping Conditions

Wet Ice

Protein Length

560

NCBI Gene Symbol

AATF

NCBI GB Accession Number

AATF

Host or Source

Rabbit

Protein Name

Protein AATF

Nucleotide Accession Number

NM_012138

Peptide Sequence

EEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEE

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