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NKX2-8 Antibody - C-terminal region : HRP (ARP31856_P050-HRP)

Selected Variant

ARP31856_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

NK2 homeobox 8

Gene Aliases

NKX2H, NKX2.8, Nkx2-9

Gene ID

26257

Swiss Prot

O15522

Accession Number

NP_055175

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NKX2-8

Target

A murine NKX2-8 was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor. Nkx2.8 bound to the active AFP promoter, and antisense inhibition of Nkx2.8 mRNA translation selectively reduced expression of both the endogenous human AFP gene and transfected reporters containing the rat AFP promoter.

Partner Proteins

NKX2-8

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

26kDa

References & Citations

Kajiyama, Y., et al., (2002) Mol. Cell. Biol. 22 (17), 6122-6130

Shipping Conditions

Wet Ice

Protein Length

239

NCBI Gene Symbol

NKX2-8

NCBI GB Accession Number

NKX2-8

Host or Source

Rabbit

Protein Name

Homeobox protein Nkx-2.8

Nucleotide Accession Number

NM_014360

Peptide Sequence

GTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAYQHLASPALVSWNW

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