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GATA2 Antibody - N-terminal region : HRP (ARP31855_T100-HRP)

Selected Variant

ARP31855_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

GATA binding protein 2

Gene Aliases

DCML, IMD21, NFE1B, MONOMAC

Gene ID

2624

Swiss Prot

P23769

Accession Number

NP_116027

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GATA2

Target

The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.

Partner Proteins

NOTCH2NL; KRTAP10-3; KRTAP10-9; KRT40; PRR20A; ADAMTSL4; TRAF1; PSMA3; MDFI; GOLGA2; FHL3; TRIM23; AKT1; BMI1; SPI1; SMAD4; ELAVL1; KAT2A; EP300; MED1; POU1F1; POU2AF1; ZBTB32; ZFPM1; ZBTB16; HDAC5; HDAC3; HHEX; RARA; RXRA; MAPK1; JUN; CEBPA; STAT3; PML

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

GATA2 is strongly supported by BioGPS gene expression data to be expressed in K562

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Tsuzuki, S., et al., (2004) Mol. Cell. Biol. 24 (15), 6824-6836

Shipping Conditions

Wet Ice

Protein Length

480

NCBI Gene Symbol

GATA2

NCBI GB Accession Number

GATA2

Host or Source

Rabbit

Protein Name

Endothelial transcription factor GATA-2

Nucleotide Accession Number

NM_032638

Peptide Sequence

PYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSA

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