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PDK2 Antibody - middle region : Biotin (ARP31778_P050-Biotin)

Product Specifications

Gene Name

Pyruvate dehydrogenase kinase, isozyme 2

Gene Aliases

PDHK2, PDKII

Gene ID

5164

Swiss Prot

Q15119

Accession Number

NP_002602

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PDK2

Target

PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

Partner Proteins

VSIG4; DLAT; ISOC2; HIC2; SGK1; PDK2; PDK1; PDHA1; PDHX; AKT1; HTT

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

PDK2 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 77%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Hiromasa, Y., (2008) Biochemistry 47 (8), 2312-2324

Shipping Conditions

Wet Ice

Protein Length

407

NCBI Gene Symbol

PDK2

NCBI GB Accession Number

PDK2

Host or Source

Rabbit

Protein Name

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial

Nucleotide Accession Number

NM_002611

Peptide Sequence

ELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKI

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