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FBXL11 Antibody - N-terminal region : Biotin (ARP31697_P050-Biotin)

Selected Variant

ARP31697_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Lysine (K) -specific demethylase 2A

Gene Aliases

FBL7, CXXC8, FBL11, FBXL11, JHDM1A, LILINA

Gene ID

22992

Swiss Prot

Q9Y2K7-3

Accession Number

AAH47486

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL11

Target

FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box) . The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats

Partner Proteins

RB1; E2F1; EED; SKP1; MPG; ZNF512B; UBE2G2; SMAD7; SMAD3; HIST3H3; HIST2H3C; KIAA0368; ELAVL1; UBC; BCL6; FOS; RELA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

86kDa

References & Citations

Strausberg, R.L., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903

Shipping Conditions

Wet Ice

Protein Length

782

NCBI Gene Symbol

KDM2A

NCBI GB Accession Number

KDM2A

Host or Source

Rabbit

Protein Name

Lysine-specific demethylase 2A

Nucleotide Accession Number

NM_001256405

Peptide Sequence

RIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNANFVTF

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