SCMH1 Antibody - middle region : FITC (ARP31693_P050-FITC)
Product Specifications
Gene Name
Sex comb on midleg homolog 1 (Drosophila)
Gene Aliases
Scml3
Gene ID
22955
Swiss Prot
Q96GD3-4
Accession Number
NP_036368
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SCMH1
Target
SCMH1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Partner Proteins
UBQLN1; RNF2; MAGEA12; BMI1; UBQLN4; PHC3; CBX4; PCGF2; PHC2; PHC1; MAML3; LZTR1; PCBD1; EWSR1; TMEM11; SCMH1; MOB4; TOB1; POLR2M; LYPLA2; GMNN; HK1; Cbx2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 86%; Yeast: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
65kDa
References & Citations
Olsen, J.V., (2006) Cell 127 (3), 635-648
Shipping Conditions
Wet Ice
Protein Length
591
NCBI Gene Symbol
SCMH1
NCBI GB Accession Number
SCMH1
Host or Source
Rabbit
Protein Name
Polycomb protein SCMH1
Nucleotide Accession Number
NM_012236
Peptide Sequence
LTGDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRK
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