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KIN Antibody - middle region : HRP (ARP31690_P050-HRP)

Selected Variant

ARP31690_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

KIN, antigenic determinant of recA protein homolog (mouse)

Gene Aliases

BTCD, Rts2, KIN17

Gene ID

22944

Swiss Prot

O60870

Accession Number

NP_036443

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human KIN

Target

Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.

Partner Proteins

UBC; HECW2; RPA1; PCNA; METTL22; Bud13; RPA2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

KIN is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 85%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Rabbit: 85%; Rat: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Despras, E., et al., (2003) Radiat.Res.159 (6),748-758

Shipping Conditions

Wet Ice

Protein Length

393

NCBI Gene Symbol

KIN

NCBI GB Accession Number

KIN

Host or Source

Rabbit

Protein Name

DNA/RNA-binding protein KIN17

Nucleotide Accession Number

NM_012311

Peptide Sequence

LKTIGSSASVKRKESSQSSTQSKEKKKKKSALDEIMEIEEEKKRTARTDY

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