SUPT16H Antibody - N-terminal region : Biotin (ARP31526_T100-Biotin)
Product Specifications
Gene Name
Suppressor of Ty 16 homolog (S. cerevisiae)
Gene Aliases
CDC68, SPT16, FACTP140, SPT16/CDC68
Gene ID
11198
Swiss Prot
Q9Y5B9
Accession Number
EAW66386
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SUPT16H
Target
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H.
Partner Proteins
HIST1H2AB; UBC; SUMO2; ATRX; SUMO1; NEDD8; RNF20; PAF1; EED; RNF2; BMI1; rev; FTH1; QRICH1; SRPK2; ICAM1; CD81; IGSF8; PNKP; VCP; FMNL1; SSRP1; ESR1; CENPA; LEO1; RBM25; PRPF6; NCSTN; RTF1; ACIN1; PSIP1; USP39; PRPF8; SF3A1; SAP18; CTR9; DDX21; PRPF3; PRP
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Sample Type
SUPT16H is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
66kDa
Shipping Conditions
Wet Ice
Protein Length
602
NCBI Gene Symbol
SUPT16H
NCBI GB Accession Number
SUPT16H
Host or Source
Rabbit
Protein Name
FACT complex subunit SPT16
Nucleotide Accession Number
NM_007192
Peptide Sequence
ASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIK
Subunit
SPT16
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