MYST2 Antibody - N-terminal region : Biotin (ARP31518_P050-Biotin)
Product Specifications
Gene Name
K (lysine) acetyltransferase 7
Gene Aliases
HBO1, HBOA, MYST2, ZC2HC7
Gene ID
11143
Swiss Prot
O95251
Accession Number
NP_008998
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MYST2
Target
MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.
Partner Proteins
UBC; RNF2; EZH2; VIM; CDK11B; APP; HAP1; BARD1; LRIF1; ING4; JADE1; CSNK1E; DYNC1I1; CDT1; tat; HIST1H4A; HIST1H3A; HIST2H2AC; GMNN; ORC2; MCM2; CDC6; JUN; KIAA1377; CEP70; CBX8; CAAP1; KCTD13; PPID; WDR33; NINL; ZBTB8B; HOOK2; KATNBL1; POLB; CALCOCO2; AT
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
71kDa
References & Citations
Wu, Z.Q. (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (6), 1919-1924
Shipping Conditions
Wet Ice
Protein Length
611
NCBI Gene Symbol
KAT7
NCBI GB Accession Number
KAT7
Host or Source
Rabbit
Protein Name
Histone acetyltransferase KAT7
Nucleotide Accession Number
NM_007067
Peptide Sequence
MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLS
Frequently Asked Questions
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