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TBR1 Antibody - middle region : Biotin (ARP31497_P050-Biotin)

Product Specifications

Gene Name

T-box, brain, 1

Gene Aliases

IDDAS, TBR-1, TES-56

Gene ID

10716

Swiss Prot

Q16650

Accession Number

NP_006584

Host

Rabbit

Reactivity

Human, Mouse, Cow, Dog, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TBR1

Target

This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

Partner Proteins

UBC; CASK; TSPYL2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Human: 100%; Mouse: 86%; Pig: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

References & Citations

Hillier, L.W., (2005) Nature 434 (7034), 724-731

Shipping Conditions

Wet Ice

Protein Length

682

NCBI Gene Symbol

TBR1

NCBI GB Accession Number

TBR1

Host or Source

Rabbit

Protein Name

T-box brain protein 1

Nucleotide Accession Number

NM_006593

Peptide Sequence

MAGANPYLGEEAEGLAAERSPLPPGAAEDAKPKDLSDSSWIETPSSIKSI

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