SAP18 Antibody - N-terminal region: FITC (ARP31468_P050-FITC)
Product Specifications
Gene Name
Sin3A-associated protein, 18kDa
Gene Aliases
SAP18P, 2HOR0202
Gene ID
10284
Swiss Prot
O00422
Accession Number
NP_005861
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human SAP18
Target
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.
Partner Proteins
INCA1; RBM39; UBC; RNF2; SUZ12; BMI1; CSNK2A2; MAGOH; EIF4A3; VCP; NFIA; SEPT2; MYO1C; IK; HNRNPU; HNRNPC; GTF3C1; SEPT7; CDC5L; U2AF1; SNRPD2; SMARCC2; SMARCB1; SRSF7; SRSF5; SRSF3; SRSF1; SAFB; S100A9; PSAP; NHP2L1; TPR; TFPI; SURF4; SSRP1; SSR3; LOC255
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
16kDa
Shipping Conditions
Wet Ice
Protein Length
153
NCBI Gene Symbol
SAP18
Protein Name
Histone deacetylase complex subunit SAP18
Nucleotide Accession Number
NM_005870
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