AKAP8 Antibody - middle region: Biotin (ARP31467_P050-Biotin)
Product Specifications
Gene Name
A kinase (PRKA) anchor protein 8
Gene Aliases
AKAP-8, AKAP95, AKAP 95, AKAP-95
Gene ID
10270
Swiss Prot
O43823
Accession Number
NP_005849
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human AKAP8
Target
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP8 is a member of the AKAP family. It is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
SUMO2; UBC; RPA3; RPA2; RPA1; BMI1; RNF2; EZH2; HIPK4; HDAC11; CSNK2A1; MYC; ESR1; BARD1; LRRK2; CAND1; COPS5; CUL3; HNRNPA1; ELAVL1; Mis12; Aurkb; TADA2A; CASP3; DDX5; PRKAR2A; CCND1; RELA; CCND3; CCND2; MCM2; AMY1C; AMY1A
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
AKAP8 is strongly supported by BioGPS gene expression data to be expressed in HEK293T
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Pig: 86%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
76kDa
Shipping Conditions
Wet Ice
Protein Length
692
NCBI Gene Symbol
AKAP8
Protein Name
A-kinase anchor protein 8
Nucleotide Accession Number
NM_005858
Curated Selection
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