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TRIM28 Antibody - N-terminal region : Biotin (ARP31460_P050-Biotin)

Product Specifications

Gene Name

Tripartite motif containing 28

Gene Aliases

KAP1, TF1B, RNF96, TIF1B, PPP1R157

Gene ID

10155

Swiss Prot

Q13263

Accession Number

NP_005753

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM28

Target

TRIM28 mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. TRIM28 localizes to the nucleus and is thought to associate with specific chromatin regions. It is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

WWOX; ERLIN2; HUWE1; SUMO1; UBC; SPRTN; SENP7; HAUS2; MAGEC2; CBX5; WHSC1; UBE2I; AURKA; SUMO2; SUMO3; RNF4; CEP250; TRIM28; HIF1A; CHD3; ATM; ZNF350; STAU1; HIST3H3; LYN; NEDD8; MDM2; ZBTB1; RPA3; RPA2; RPA1; RNF2; SUZ12; EZH2; BMI1; EED; BRCC3; WRNIP1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TRIM28 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

References & Citations

Kamitani, S., (2008) Biochem. Biophys. Res. Commun. 370 (2), 366-370

Shipping Conditions

Wet Ice

Protein Length

835

NCBI Gene Symbol

TRIM28

NCBI GB Accession Number

TRIM28

Host or Source

Rabbit

Protein Name

Transcription intermediary factor 1-beta

Nucleotide Accession Number

NM_005762

Peptide Sequence

AASAAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSP

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