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TRIM28 Antibody - N-terminal region : HRP (ARP31460_P050-HRP)

Product Specifications

Gene Name

Tripartite motif containing 28

Gene Aliases

KAP1, TF1B, RNF96, TIF1B, PPP1R157

Gene ID

10155

Swiss Prot

Q13263

Accession Number

NP_005753

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM28

Target

TRIM28 mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. TRIM28 localizes to the nucleus and is thought to associate with specific chromatin regions. It is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

WWOX; ERLIN2; HUWE1; SUMO1; UBC; SPRTN; SENP7; HAUS2; MAGEC2; CBX5; WHSC1; UBE2I; AURKA; SUMO2; SUMO3; RNF4; CEP250; TRIM28; HIF1A; CHD3; ATM; ZNF350; STAU1; HIST3H3; LYN; NEDD8; MDM2; ZBTB1; RPA3; RPA2; RPA1; RNF2; SUZ12; EZH2; BMI1; EED; BRCC3; WRNIP1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TRIM28 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

References & Citations

Kamitani, S., (2008) Biochem. Biophys. Res. Commun. 370 (2), 366-370

Shipping Conditions

Wet Ice

Protein Length

835

NCBI Gene Symbol

TRIM28

NCBI GB Accession Number

TRIM28

Host or Source

Rabbit

Protein Name

Transcription intermediary factor 1-beta

Nucleotide Accession Number

NM_005762

Peptide Sequence

AASAAAASAAAASAASGSPGPGEGSAGGEKRSTAPSAAASASASAAASSP

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