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TSFM Antibody - middle region : Biotin (ARP31455_P050-Biotin)

Product Specifications

Gene Name

Ts translation elongation factor, mitochondrial

Gene Aliases

EFTS, EFTSMT

Gene ID

10102

Swiss Prot

P43897

Accession Number

NP_005717

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TSFM

Target

The TSFM protein is a mitochondrial translation elongation factor. Synthesis of the 13 mitochondrial-encoded proteins occurs on a dedicated mitochondrial translation apparatus similar to that found in prokaryotes and requires, in addition to the tRNAs and rRNAs encoded in mtDNA, the concerted action of several translation factors and a large number of mitochondrial ribosomal proteins, all of which are encoded by nuclear genes.Synthesis of the 13 mitochondrial-encoded proteins occurs on a dedicated mitochondrial translation apparatus similar to that found in prokaryotes and requires, in addition to the tRNAs and rRNAs encoded in mtDNA, the concerted action of several translation factors and a large number of mitochondrial ribosomal proteins, all of which are encoded by nuclear genes. The TSFM gene encodes a mitochondrial translation elongation factor (Smeitink et al., 2006 [PubMed 17033963]) .[supplied by OMIM].

Partner Proteins

UBC; SUMO2; LIG4; C1QBP; MRRF; ACOT13; CDV3; MTRNR2L1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TSFM is strongly supported by BioGPS gene expression data to be expressed in 721_B, HeLa, MCF7 There is BioGPS gene expression data showing that TSFM is expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

References & Citations

Smeitink, J.A., (2006) Am. J. Hum. Genet. 79 (5), 869-877

Shipping Conditions

Wet Ice

Protein Length

346

NCBI Gene Symbol

TSFM

NCBI GB Accession Number

TSFM

Host or Source

Rabbit

Protein Name

Elongation factor Ts, mitochondrial

Nucleotide Accession Number

NM_005726

Peptide Sequence

GTMMHCQTLKDQPSAYSKGFLNSSELSGLPAGPDREGSLKDQLALAIGKL

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