PQBP1 Antibody - middle region : Biotin (ARP31454_T100-Biotin)
Product Specifications
Gene Name
Polyglutamine binding protein 1
Gene Aliases
SHS, MRX2, MRX55, MRXS3, MRXS8, NPW38, RENS1
Gene ID
10084
Swiss Prot
O60828-5
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PQBP1
Target
This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Partner Proteins
MAPRE1; GOLGA2; LZTS2; UBC; APBB1; WDR77; AQR; HNRNPH2; MRPL53; SLIRP; SRPRB; SUGP1; MRPS28; RPS6KA6; HRSP12; SCO2; ZC3H11A; UBL4A; VDAC3; RRBP1; RPS28; RBMS1; NDUFA7; IDH3G; APP; WBP11; RCVRN; LNX1; SF3A2; SFTPC; TXNL4A; TLX3; LRIF1; MED31; POLR2A; C14or
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
30kDa
References & Citations
Waragai, M. et al., (1999) Hum Mol Genet. 8 (6) :977-87
Shipping Conditions
Wet Ice
Protein Length
265
NCBI Gene Symbol
PQBP1
NCBI GB Accession Number
PQBP1
Host or Source
Rabbit
Protein Name
Polyglutamine-binding protein 1
Peptide Sequence
PSCGLPYYWNADREEGKERRHHRREELAPYPKSKKAVSRKDEELDPMDPS
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