HDAC6 Antibody - N-terminal region: HRP (ARP31451_P050-HRP)
Product Specifications
Gene Name
Histone deacetylase 6
Gene Aliases
HD6, JM21, CPBHM, PPP1R90
Gene ID
10013
Swiss Prot
Q9UBN7
Accession Number
AAH05872
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC6
Target
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Partner Proteins
HSP90B1; ACTB; UBC; TRIM50; MYH10; DYNC1H1; DDIT3; ELAVL1; MAPK3; MAPK1; RUNX2; TUBA1B; SUMO1; RANBP9; NEDD8; ADRB2; ATXN3; MEF2B; SQSTM1; HSP90AA1; RASSF2; SLMAP; SAV1; CTTNBP2NL; BAG3; SETD8; TUBB; HSPA8; HSPA6; HSPA5; HSPA4; HSPA2; HSPA1L; DNAJA1; ETV6
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB, CHIP, IHC
Purification
Affinity Purified
Sample Type
There is BioGPS gene expression data showing that HDAC6 is expressed in HEK293T
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
131kDa, 17 kD
Shipping Conditions
Wet Ice
Protein Length
1215
NCBI Gene Symbol
HDAC6
Protein Name
HDAC6 protein EMBL AAH05872.1
Nucleotide Accession Number
NM_006044
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