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GTF2H3 Antibody - N-terminal region : Biotin (ARP31438_P050-Biotin)

Product Specifications

Gene Name

General transcription factor IIH, polypeptide 3, 34kDa

Gene Aliases

P34, BTF2, TFB4, TFIIH

Gene ID

2967

Swiss Prot

Q13889

Accession Number

NP_001507

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2H3

Target

GTranscription Factor Antibodies2H3 interacts with HIV-1 Tat as a component of the HIV-1 transcription pre-initiation complex, but is released from the elongation complex which includes P-TEFb. It synergizes with HIV-1 Tat to induce transcription elongation from the HIV-1 LTR promoter.

Partner Proteins

GTF2H2C_2; UBC; RPA3; RPA2; RPA1; CDK7; HEATR5A; MNAT1; GTF2H4; GTF2H2; GTF2H1; ERCC3; XBP1P1; ERCC2; AR

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

GTF2H3 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Zhou, M., et al., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (22), 12666-12671

Shipping Conditions

Wet Ice

Protein Length

308

NCBI Gene Symbol

GTF2H3

NCBI GB Accession Number

GTF2H3

Host or Source

Rabbit

Protein Name

General transcription factor IIH subunit 3

Nucleotide Accession Number

NM_001516

Peptide Sequence

VIASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSAN

Subunit

3

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