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GTF2H3 Antibody - N-terminal region : HRP (ARP31438_P050-HRP)

Selected Variant

ARP31438_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

General transcription factor IIH, polypeptide 3, 34kDa

Gene Aliases

P34, BTF2, TFB4, TFIIH

Gene ID

2967

Swiss Prot

Q13889

Accession Number

NP_001507

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2H3

Target

GTranscription Factor Antibodies2H3 interacts with HIV-1 Tat as a component of the HIV-1 transcription pre-initiation complex, but is released from the elongation complex which includes P-TEFb. It synergizes with HIV-1 Tat to induce transcription elongation from the HIV-1 LTR promoter.

Partner Proteins

GTF2H2C_2; UBC; RPA3; RPA2; RPA1; CDK7; HEATR5A; MNAT1; GTF2H4; GTF2H2; GTF2H1; ERCC3; XBP1P1; ERCC2; AR

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

GTF2H3 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Zhou, M., et al., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (22), 12666-12671

Shipping Conditions

Wet Ice

Protein Length

308

NCBI Gene Symbol

GTF2H3

NCBI GB Accession Number

GTF2H3

Host or Source

Rabbit

Protein Name

General transcription factor IIH subunit 3

Nucleotide Accession Number

NM_001516

Peptide Sequence

VIASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSAN

Subunit

3

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