SPI1 Antibody - N-terminal region : HRP (ARP31420_P050-HRP)
Selected Variant
ARP31420_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Spi-1 proto-oncogene
Gene Aliases
OF, PU.1, SFPI1, SPI-1, SPI-A
Gene ID
6688
Swiss Prot
P17947
Accession Number
NP_001074016.1
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human SPI1
Target
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Pig: 100%; Rabbit: 100%; Rat: 77%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
26kDa
Shipping Conditions
Wet Ice
Protein Length
245
NCBI Gene Symbol
SPI1
NCBI GB Accession Number
SPI1
Host or Source
Rabbit
Protein Name
Transcription factor PU.1
Nucleotide Accession Number
NM_001080547.1
Peptide Sequence
MEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPH
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