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ISL1 Antibody - C-terminal region: HRP (ARP31300_P050-HRP)

Product Specifications

Gene Name

ISL LIM homeobox 1

Gene Aliases

Isl-1, ISLET1

Gene ID

3670

Swiss Prot

P61371

Accession Number

NP_002193

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human ISL1

Target

ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation.

Partner Proteins

ZNF511; KDM1A; RELA; SMAD3; CDKN2B; CDK6; APP; COPS5; SSBP4; LHX4; LDB2; ISL2; PECR; LDB1; LHX1; LHX3; LMX1A; RLIM; LMO2; ESR1; NR2F1; ISL1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

Shipping Conditions

Wet Ice

Protein Length

349

NCBI Gene Symbol

ISL1

Protein Name

Insulin gene enhancer protein ISL-1

Nucleotide Accession Number

NM_002202

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