CREB1 Antibody - N-terminal region : Biotin (ARP31264_T100-Biotin)

Product Specifications

Gene Name

CAMP responsive element binding protein 1

Gene Aliases

CREB, CREB-1

Gene ID

1385

Swiss Prot

P16220

Accession Number

NP_604391

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CREB1

Target

CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Partner Proteins

UBC; NCOR1; CREM; CREBBP; RPS6KA1; NR5A2; EP300; DEAF1; TP53; CREB1; PRKG1; YAP1; MAPK14; MEIS1; DAXX; TSSK4; AKT1; ATR; SIRT1; SRA1; DR1; ATF7; GSK3B; GSK3A; ATXN3; DNMT3B; RPS6KA5; YY1; RGS13; JUN; HDAC2; HDAC1; CCDC6; PPP1CA; SUMO1; TAF4; POU2F1; MYOD1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Sample Type

CREB1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 87%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.