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CEBPB Antibody - C-terminal region : Biotin (ARP31259_P050-Biotin)

Product Specifications

Gene Name

CCAAT/enhancer binding protein (C/EBP), beta

Gene Aliases

TCF5, IL6DBP, NF-IL6, C/EBP-beta

Gene ID

1051

Swiss Prot

P17676

Accession Number

NP_005185

Host

Rabbit

Reactivity

Human, Cow, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CEBPB

Target

The protein encoded by this intronless gene, CEBPB, is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.

Partner Proteins

CEBPA; UBC; EGR1; EP300; TP63; RB1; RELA; DAXX; CASP8; CASP1; SMARCA2; HDAC1; SMARCC1; SMARCB1; SMARCA4; SMARCA5; TAF9; ELAVL1; SUMO2; TRIM28; CEBPB; ATF3; CARM1; GSK3B; SUMO1; KAT2A; HDAC9; KAT2B; NCOR2; NCOR1; STAT3; PPARG; NRF1; CREBBP; ATF2; EHMT2; SP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Rabbit: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Chen, C., et al., (2004) J. Biol. Chem. 279 (27), 27948-27956

Shipping Conditions

Wet Ice

Protein Length

345

NCBI Gene Symbol

CEBPB

NCBI GB Accession Number

CEBPB

Host or Source

Rabbit

Protein Name

CCAAT/enhancer-binding protein beta

Nucleotide Accession Number

NM_005194

Peptide Sequence

ADAKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKS

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