CEBPB Antibody - C-terminal region : HRP (ARP31259_P050-HRP)
Product Specifications
Gene Name
CCAAT/enhancer binding protein (C/EBP), beta
Gene Aliases
TCF5, IL6DBP, NF-IL6, C/EBP-beta
Gene ID
1051
Swiss Prot
P17676
Accession Number
NP_005185
Host
Rabbit
Reactivity
Human, Cow, Dog, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CEBPB
Target
The protein encoded by this intronless gene, CEBPB, is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Partner Proteins
CEBPA; UBC; EGR1; EP300; TP63; RB1; RELA; DAXX; CASP8; CASP1; SMARCA2; HDAC1; SMARCC1; SMARCB1; SMARCA4; SMARCA5; TAF9; ELAVL1; SUMO2; TRIM28; CEBPB; ATF3; CARM1; GSK3B; SUMO1; KAT2A; HDAC9; KAT2B; NCOR2; NCOR1; STAT3; PPARG; NRF1; CREBBP; ATF2; EHMT2; SP
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Rabbit: 92%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
36kDa
References & Citations
Chen, C., et al., (2004) J. Biol. Chem. 279 (27), 27948-27956
Shipping Conditions
Wet Ice
Protein Length
345
NCBI Gene Symbol
CEBPB
NCBI GB Accession Number
CEBPB
Host or Source
Rabbit
Protein Name
CCAAT/enhancer-binding protein beta
Nucleotide Accession Number
NM_005194
Peptide Sequence
ADAKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKS
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