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GABPB2 Antibody - middle region : HRP (ARP31189_P050-HRP)

Selected Variant

ARP31189_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

GA binding protein transcription factor, beta subunit 1

Gene Aliases

E4TF1, GABPB, BABPB2, E4TF1B, GABPB2, NRF2B1, NRF2B2, GABPB-1, E4TF1-47, E4TF1-53

Gene ID

2553

Swiss Prot

Q06547

Accession Number

NP_005245

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GABPB2

Target

GABPB2 is the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

FAM90A1; RBM11; RSPH14; TDRD7; POGZ; LMO4; TRAF2; SNRPB2; SNRPA; LMO1; UBC; MAGEB18; RYBP; YAF2; YY1; GABPA; IL16; DHX16; CIC; LMO3; USO1; FANCG; BAI2; HCFC1; ATF1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

GABPB1 is strongly supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42kDa

References & Citations

Crook, M.F., (2008) FASEB J. 22 (1), 225-235

Shipping Conditions

Wet Ice

Protein Length

395

NCBI Gene Symbol

GABPB1

NCBI GB Accession Number

GABPB1

Host or Source

Rabbit

Protein Name

GA-binding protein subunit beta-1

Nucleotide Accession Number

NM_005254

Peptide Sequence

EPPAKRQCIEIIENRVESAEIEEREALQKQLDEANREAQKYRQQLLKKEQ

Subunit

Beta-1

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